The earliest source mentioning Jews in Radkersburg records several families. A woman by the name Seld, her husband Isaak and their son Jacob, were mentioned in a law-suit. The synagogue was probably in the Judengasse.
The Jews of Radkersburg buried their dead in Graz and prayed in the synagogue there, thus paying taxes to the community there. The main source of income was moneylending, often to noblemen and local burghers. Radkersburg was one of the four Styrian places where a Judenmeister (representative of the Jewish community) officiated in the late 15th century. Rabbi Mosche (Musch) is documented during 1441 and 1478.
The Jews were expelled from Radkersburg in 1496; the Jews sold their houses and left until 1500. A chapel dedicated to the Virgin Mary was erected on the site of the synagogue.